Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
KIRC | rs13220248 | chr6:2395110 | G/C | 2.84E-9 | 521 | 40 | 40.58 | 12.07 | KM Plot |
KIRC | rs13220395 | chr6:26055368 | A/G | 1.06E-9 | 527 | 3.37 | 36.12 | 41.13 | KM Plot |
KIRC | rs13220488 | chr6:25896907 | A/G | 1.42E-9 | 519 | 41.27 | 36.87 | 2.38 | KM Plot |
KIRC | rs1322188 | chr6:165343216 | A/G | 3.58E-5 | 522 | 15.83 | 39.17 | 39.85 | KM Plot |
KIRC | rs13234396 | chr7:7742919 | G/A | 4.8E-5 | 527 | 38.1 | 48.63 | 5.47 | KM Plot |
KIRC | rs13241780 | chr7:156193575 | C/T | 4.85E-5 | 501 | 39.38 | 43.68 | 22.83 | KM Plot |
KIRC | rs13247039 | chr7:7760290 | A/G | 3.59E-5 | 522 | 39.38 | 42.33 | 5.47 | KM Plot |
KIRC | rs13296663 | chr9:6713143 | G/A | 6.72E-6 | 521 | 40.78 | 42.33 | 19.68 | KM Plot |
KIRC | rs13315308 | chr3:139780549 | A/G | 3.8E-6 | 519 | 40.28 | 33.97 | 3.67 | KM Plot |
KIRC | rs13329084 | chr15:44151063 | A/G | 1.48E-14 | 527 | 2.07 | 36.97 | 40.8 | KM Plot |
KIRC | rs13355707 | chr5:109993750 | A/G | 7.6E-6 | 527 | 35.03 | 29.43 | 40.8 | KM Plot |
KIRC | rs1349131 | chr2:2969422 | C/G | 8.92E-6 | 527 | 43.9 | 40 | 20.12 | KM Plot |
KIRC | rs137927562 | chr8:67261542 | GAATA/G | 0 | 524 | 39.38 | 40 | 0.6 | KM Plot |
KIRC | rs138381095 | chr11:36133204 | G/A | 1.49E-5 | 518 | 37.77 | 48.2 | 9.18 | KM Plot |
KIRC | rs138742157 | chr11:34759989 | G/T | 1.77E-7 | 517 | 39.53 | 39.17 | 3.3 | KM Plot |